Prophylaxis and Treatment of Postoperative Nausea and Vomiting (PONV)

Postoperative nausea and vomiting

Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discus...

Postoperative Nausea and Vomiting

Ramosetron for the prevention of postoperative nausea and vomiting (PONV): a meta-analysis

BACKGROUND Postoperative nausea and vomiting (PONV) remains a challenge for patients and health professionals despite various newly developed prophylactic interventions. We reviewed the efficacy and safety of ramosetron in randomized controlled trials (RCTs) for the prevention of PONV. METHODS We reviewed 18 randomized controlled trials investigating the efficacy and safety of ramosetron in c...

Prevention and treatment of postoperative nausea and vomiting

Side effects of surgical procedures are frequent at postoperative, pain, nausea and vomiting are common. Although there is a major concern with prevention of pain, vomiting at postoperative occurs in about 30% of patients.(1) Postoperative nausea and vomiting (PONV) are defined as development of episodes of nausea and emesis after a surgical act and before hospital discharge. Nausea is defined ...

Controlling postoperative nausea and vomiting

Postoperative nausea and vomiting (PNV) in the ambulatory surgical unit is a continuing and vexing problem. Delayed discharges and patient discomfort have major impact in an outpatient setting. An understanding of the causes and aetiologies of PNV including anaesthetic, surgical and patient factors is critically important in the management of these patients. Therapy begins with a good history, ...